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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
26.67
Human Site:
T456
Identified Species:
45.13
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
T456
R
K
H
H
F
F
K
T
I
N
F
P
R
L
E
Chimpanzee
Pan troglodytes
XP_526333
553
62171
T456
R
K
H
H
F
F
K
T
I
N
F
P
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
T456
R
K
H
H
F
F
K
T
I
N
F
P
R
L
E
Dog
Lupus familis
XP_542813
553
62196
T456
R
Q
H
P
F
F
K
T
I
N
F
A
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
N450
K
R
H
P
F
F
R
N
M
N
F
K
R
L
E
Rat
Rattus norvegicus
Q62833
590
67764
N450
K
R
H
P
F
F
R
N
M
N
F
K
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
E457
R
A
N
A
L
F
R
E
I
N
W
R
Q
L
E
Chicken
Gallus gallus
XP_426681
551
62925
T452
R
K
H
S
F
F
K
T
I
N
F
H
R
L
E
Frog
Xenopus laevis
NP_001131051
551
62674
S453
R
K
H
A
F
F
K
S
I
N
F
Q
R
L
E
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
S451
R
K
H
E
W
F
K
S
I
N
F
A
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
F573
Q
D
V
M
A
H
P
F
F
H
S
T
Q
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
T472
R
A
H
P
F
F
N
T
A
D
T
V
T
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
G379
R
L
G
S
G
L
S
G
A
E
E
I
K
Q
H
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
D673
R
A
H
P
F
F
A
D
I
D
W
E
A
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
100
100
80
N.A.
53.3
53.3
N.A.
40
86.6
80
73.3
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
66.6
86.6
86.6
86.6
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
15
8
0
8
0
15
0
0
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
15
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
8
0
8
8
8
0
0
72
% E
% Phe:
0
0
0
0
72
86
0
8
8
0
65
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
79
22
0
8
0
0
0
8
0
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
65
0
0
8
0
0
0
% I
% Lys:
15
43
0
0
0
0
50
0
0
0
0
15
8
0
8
% K
% Leu:
0
8
0
0
8
8
0
0
0
0
0
0
0
86
0
% L
% Met:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
15
0
72
0
0
0
0
8
% N
% Pro:
0
0
0
36
0
0
8
0
0
0
0
22
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
8
15
8
0
% Q
% Arg:
79
15
0
0
0
0
22
0
0
0
0
8
65
0
8
% R
% Ser:
0
0
0
15
0
0
8
15
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
8
8
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _